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Prediction of conformational epitopes with the use of a knowledge-based energy function and geometrically related neighboring residue characteristics

BACKGROUND: A conformational epitope (CE) in an antigentic protein is composed of amino acid residues that are spatially near each other on the antigen's surface but are separated in sequence; CEs bind their complementary paratopes in B-cell receptors and/or antibodies. CE predication is used d...

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Detalles Bibliográficos
Autores principales: Lo, Ying-Tsang, Pai, Tun-Wen, Wu, Wei-Kuo, Chang, Hao-Teng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599093/
https://www.ncbi.nlm.nih.gov/pubmed/23514199
http://dx.doi.org/10.1186/1471-2105-14-S4-S3