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Conformational epitope matching and prediction based on protein surface spiral features

BACKGROUND: A conformational epitope (CE) is composed of neighboring amino acid residues located on an antigenic protein surface structure. CEs bind their complementary paratopes in B-cell receptors and/or antibodies. An effective and efficient prediction tool for CE analysis is critical for the dev...

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Detalles Bibliográficos
Autores principales: Lo, Ying-Tsang, Shih, Tao-Chuan, Pai, Tun-Wen, Ho, Li-Ping, Wu, Jen-Leih, Chou, Hsin-Yiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165135/
https://www.ncbi.nlm.nih.gov/pubmed/34058977
http://dx.doi.org/10.1186/s12864-020-07303-5