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Immunogenic properties of amyloid beta oligomers

BACKGROUND: The central molecule in the pathogenesis of Alzheimer’s disease (AD) is believed to be a small-sized polypeptide – beta amyloid (Aβ) which has an ability to assemble spontaneously into oligomers. Various studies concerning therapeutic and prophylactic approaches for AD are based on the i...

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Detalles Bibliográficos
Autores principales: Dalgediene, Indre, Lasickiene, Rita, Budvytyte, Rima, Valincius, Gintaras, Morkuniene, Ramune, Borutaite, Vilmante, Zvirbliene, Aurelija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599114/
https://www.ncbi.nlm.nih.gov/pubmed/23432787
http://dx.doi.org/10.1186/1423-0127-20-10