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Estimation of CpG coverage in whole methylome next-generation sequencing studies
BACKGROUND: Methylation studies are a promising complement to genetic studies of DNA sequence. However, detailed prior biological knowledge is typically lacking, so methylome-wide association studies (MWAS) will be critical to detect disease relevant sites. A cost-effective approach involves the nex...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599116/ https://www.ncbi.nlm.nih.gov/pubmed/23398781 http://dx.doi.org/10.1186/1471-2105-14-50 |