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Estimation of CpG coverage in whole methylome next-generation sequencing studies

BACKGROUND: Methylation studies are a promising complement to genetic studies of DNA sequence. However, detailed prior biological knowledge is typically lacking, so methylome-wide association studies (MWAS) will be critical to detect disease relevant sites. A cost-effective approach involves the nex...

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Detalles Bibliográficos
Autores principales:	van den Oord, Edwin JCG, Bukszar, Jozsef, Rudolf, Gábor, Nerella, Srilaxmi, McClay, Joseph L, Xie, Lin Y, Aberg, Karolina A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599116/ https://www.ncbi.nlm.nih.gov/pubmed/23398781 http://dx.doi.org/10.1186/1471-2105-14-50

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