Cargando…

Mechanisms of action of naturally occurring antibodies against β-amyloid on microglia

BACKGROUND: Naturally occurring autoantibodies against amyloid-β (nAbs-Aβ) have been shown to exert beneficial effects on transgenic Alzheimer’s disease (AD) animals in vivo and on primary neurons in vitro. Not much is known about their effect on microglial cells. Our aim was to investigate the effe...

Descripción completa

Detalles Bibliográficos
Autores principales: Gold, Maike, Mengel, David, Röskam, Stephan, Dodel, Richard, Bach, Jan-Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599240/
https://www.ncbi.nlm.nih.gov/pubmed/23317003
http://dx.doi.org/10.1186/1742-2094-10-5