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Mechanisms of action of naturally occurring antibodies against β-amyloid on microglia
BACKGROUND: Naturally occurring autoantibodies against amyloid-β (nAbs-Aβ) have been shown to exert beneficial effects on transgenic Alzheimer’s disease (AD) animals in vivo and on primary neurons in vitro. Not much is known about their effect on microglial cells. Our aim was to investigate the effe...
Autores principales: | Gold, Maike, Mengel, David, Röskam, Stephan, Dodel, Richard, Bach, Jan-Philipp |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599240/ https://www.ncbi.nlm.nih.gov/pubmed/23317003 http://dx.doi.org/10.1186/1742-2094-10-5 |
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