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Elucidating the crosstalk mechanism between IFN-gamma and IL-6 via mathematical modelling
BACKGROUND: Interferon-gamma (IFN-gamma) and interleukin-6 (IL-6) are multifunctional cytokines that regulate immune responses, cell proliferation, and tumour development and progression, which frequently have functionally opposing roles. The cellular responses to both cytokines are activated via th...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599299/ https://www.ncbi.nlm.nih.gov/pubmed/23384097 http://dx.doi.org/10.1186/1471-2105-14-41 |