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Age-dependent roles of peroxisomes in the hippocampus of a transgenic mouse model of Alzheimer’s disease
BACKGROUND: Alzheimer’s Disease (AD) is a progressive neurodegenerative disease, especially affecting the hippocampus. Impairment of cognitive and memory functions is associated with amyloid β-peptide-induced oxidative stress and alterations in lipid metabolism. In this scenario, the dual role of pe...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599312/ https://www.ncbi.nlm.nih.gov/pubmed/23374228 http://dx.doi.org/10.1186/1750-1326-8-8 |