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Analysis of antibody induction upon immunization with distinct NTS-DBL1α-domains of PfEMP1 from rosetting Plasmodium falciparum parasites

BACKGROUND: Rosette-formation of Plasmodium falciparum parasitized erythrocytes is of importance in the development of severe malaria. The parasite-derived molecule PfEMP1 (Plasmodium falciparum erythrocyte membrane protein 1), central to rosetting, is suggested to be included in a multimeric vaccin...

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Detalles Bibliográficos
Autores principales: Angeletti, Davide, Albrecht, Letusa, Wahlgren, Mats, Moll, Kirsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599323/
https://www.ncbi.nlm.nih.gov/pubmed/23347690
http://dx.doi.org/10.1186/1475-2875-12-32