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Mutation spectrum in human colorectal cancers and potential functional relevance

BACKGROUND: Somatic variants, which occur in the genome of all cells, are well accepted to play a critical role in cancer development, as their accumulation in genes could affect cell proliferations and cell cycle. METHODS: In order to understand the role of somatic mutations in human colorectal can...

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Detalles Bibliográficos
Autores principales: Yin, Hongzhuan, Liang, Yichao, Yan, Zhaopeng, Liu, Baolin, Su, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599340/
https://www.ncbi.nlm.nih.gov/pubmed/23497483
http://dx.doi.org/10.1186/1471-2350-14-32