Discovery and characterization of a highly efficient enantioselective mandelonitrile hydrolase from Burkholderia cenocepacia J2315 by phylogeny-based enzymatic substrate specificity prediction

BACKGROUND: A nitrilase-mediated pathway has significant advantages in the production of optically pure (R)-(−)-mandelic acid. However, unwanted byproduct, low enantioselectivity, and specific activity reduce its value in practical applications. An ideal nitrilase that can efficiently hydrolyze mand...

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Detalles Bibliográficos
Autores principales: Wang, Hualei, Sun, Huihui, Wei, Dongzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599355/
https://www.ncbi.nlm.nih.gov/pubmed/23414071
http://dx.doi.org/10.1186/1472-6750-13-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599355/
https://www.ncbi.nlm.nih.gov/pubmed/23414071
http://dx.doi.org/10.1186/1472-6750-13-14

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