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Allosteric transition: a comparison of two models
INTRODUCTION: Two recent models are in use for analysis of allosteric drug action at receptor sites remote from orthosteric binding sites. One is an allosteric two-state mechanical model derived in 2000 by David Hall. The other is an extended operational model developed in 2007 by Arthur Christopoul...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599370/ https://www.ncbi.nlm.nih.gov/pubmed/23298758 http://dx.doi.org/10.1186/2050-6511-14-4 |