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Generalization of the normal-exponential model: exploration of a more accurate parametrisation for the signal distribution on Illumina BeadArrays

BACKGROUND: Illumina BeadArray technology includes non specific negative control features that allow a precise estimation of the background noise. As an alternative to the background subtraction proposed in BeadStudio which leads to an important loss of information by generating negative values, a b...

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Detalles Bibliográficos
Autores principales: Plancade, Sandra, Rozenholc, Yves, Lund, Eiliv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599453/
https://www.ncbi.nlm.nih.gov/pubmed/23231059
http://dx.doi.org/10.1186/1471-2105-13-329