Automated hierarchical classification of protein domain subfamilies based on functionally-divergent residue signatures

BACKGROUND: The NCBI Conserved Domain Database (CDD) consists of a collection of multiple sequence alignments of protein domains that are at various stages of being manually curated into evolutionary hierarchies based on conserved and divergent sequence and structural features. These domain models a...

Descripción completa

Detalles Bibliográficos
Autores principales: Neuwald, Andrew F, Lanczycki, Christopher J, Marchler-Bauer, Aron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599474/
https://www.ncbi.nlm.nih.gov/pubmed/22726767
http://dx.doi.org/10.1186/1471-2105-13-144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599474/
https://www.ncbi.nlm.nih.gov/pubmed/22726767
http://dx.doi.org/10.1186/1471-2105-13-144

Ejemplares similares