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Automated hierarchical classification of protein domain subfamilies based on functionally-divergent residue signatures
BACKGROUND: The NCBI Conserved Domain Database (CDD) consists of a collection of multiple sequence alignments of protein domains that are at various stages of being manually curated into evolutionary hierarchies based on conserved and divergent sequence and structural features. These domain models a...
Autores principales: | Neuwald, Andrew F, Lanczycki, Christopher J, Marchler-Bauer, Aron |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599474/ https://www.ncbi.nlm.nih.gov/pubmed/22726767 http://dx.doi.org/10.1186/1471-2105-13-144 |
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