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Genealogy of an ancient protein family: the Sirtuins, a family of disordered members

BACKGROUND: Sirtuins genes are widely distributed by evolution and have been found in eubacteria, archaea and eukaryotes. While prokaryotic and archeal species usually have one or two sirtuin homologs, in humans as well as in eukaryotes we found multiple versions and in mammals this family is compri...

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Detalles Bibliográficos
Autores principales: Costantini, Susan, Sharma, Ankush, Raucci, Raffaele, Costantini, Maria, Autiero, Ida, Colonna, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599600/
https://www.ncbi.nlm.nih.gov/pubmed/23497088
http://dx.doi.org/10.1186/1471-2148-13-60