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Tubby is required for trafficking G protein-coupled receptors to neuronal cilia

BACKGROUND: Tubby is the founding member of the tubby-like family of proteins. The naturally occurring tubby mutation in mice causes retinitis pigmentosa, hearing loss and obesity. Tubby has been proposed to function as an accessory factor in ciliary trafficking. We directly examined a role for tubb...

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Detalles Bibliográficos
Autores principales: Sun, Xun, Haley, James, Bulgakov, Oleg V, Cai, Xue, McGinnis, James, Li, Tiansen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599646/
https://www.ncbi.nlm.nih.gov/pubmed/23351594
http://dx.doi.org/10.1186/2046-2530-1-21