A recombinant scFv-FasL(ext) as a targeting cytotoxic agent against human Jurkat-Ras cancer

BACKGROUND: Targeted therapy of human cancers is an attractive approach and has been investigated with limited success. We have developed novel cytotoxic agents for targeted therapy of human cancers based on the extracellular cytotoxicity domain of CD178 (FasL) and the specificity offered by single...

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Detalles Bibliográficos
Autores principales: Chan, Derek V, Sharma, Rahul, Ju, Chiao-Ying A, Roffler, Steve R, Ju, Shyr-Te
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599744/
https://www.ncbi.nlm.nih.gov/pubmed/23497165
http://dx.doi.org/10.1186/1423-0127-20-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599744/
https://www.ncbi.nlm.nih.gov/pubmed/23497165
http://dx.doi.org/10.1186/1423-0127-20-16

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