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Amelioration of autoimmune neuroinflammation by the fusion molecule Fn14·TRAIL

BACKGROUND: Multiple sclerosis (MS) is a, T cell-mediated autoimmune disease, the management of which remains challenging. The recently described fusion protein, Fn14·TRAIL, combining the extracellular domain of Fn14 (capable of blocking the pro-inflammatory TWEAK ligand) fused to the extracellular...

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Detalles Bibliográficos
Autores principales: Prinz-Hadad, Hodaya, Mizrachi, Tehila, Irony-Tur-Sinai, Michal, Prigozhina, Tatyana B, Aronin, Alexandra, Brenner, Talma, Dranitzki-Elhalel, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599748/
https://www.ncbi.nlm.nih.gov/pubmed/23497038
http://dx.doi.org/10.1186/1742-2094-10-36