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Smoking decreases the response of human lung macrophages to double-stranded RNA by reducing TLR3 expression
BACKGROUND: Cigarette smoking is associated with increased frequency and duration of viral respiratory infections, but the underlying mechanisms are incompletely defined. We investigated whether smoking reduces expression by human lung macrophages (Mø) of receptors for viral nucleic acids and, if so...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599854/ https://www.ncbi.nlm.nih.gov/pubmed/23497334 http://dx.doi.org/10.1186/1465-9921-14-33 |