Smoking decreases the response of human lung macrophages to double-stranded RNA by reducing TLR3 expression

BACKGROUND: Cigarette smoking is associated with increased frequency and duration of viral respiratory infections, but the underlying mechanisms are incompletely defined. We investigated whether smoking reduces expression by human lung macrophages (Mø) of receptors for viral nucleic acids and, if so...

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Detalles Bibliográficos
Autores principales: Todt, Jill C, Freeman, Christine M, Brown, Jeanette P, Sonstein, Joanne, Ames, Theresa M, McCubbrey, Alexandra L, Martinez, Fernando J, Chensue, Stephen W, Beck, James M, Curtis, Jeffrey L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599854/
https://www.ncbi.nlm.nih.gov/pubmed/23497334
http://dx.doi.org/10.1186/1465-9921-14-33

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