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Molecular basis of ‘hypoxic’ breast cancer cell radio-sensitization: phytochemicals converge on radiation induced Rel signaling

BACKGROUND: Heterogeneously distributed hypoxic areas are a characteristic property of locally advanced breast cancers (BCa) and generally associated with therapeutic resistance, metastases, and poor patient survival. About 50% of locally advanced BCa, where radiotherapy is less effective are sugges...

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Detalles Bibliográficos
Autores principales: Aravindan, Sheeja, Natarajan, Mohan, Herman, Terence S, Awasthi, Vibhudutta, Aravindan, Natarajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599951/
https://www.ncbi.nlm.nih.gov/pubmed/23452621
http://dx.doi.org/10.1186/1748-717X-8-46