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Gene rearrangements in hormone receptor negative breast cancers revealed by mate pair sequencing

BACKGROUND: Chromosomal rearrangements in the form of deletions, insertions, inversions and translocations are frequently observed in breast cancer genomes, and a subset of these rearrangements may play a crucial role in tumorigenesis. To identify novel somatic chromosomal rearrangements, we determi...

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Detalles Bibliográficos
Autores principales: Jiao, Xiang, Hooper, Sean D, Djureinovic, Tatjana, Larsson, Chatarina, Wärnberg, Fredrik, Tellgren-Roth, Christian, Botling, Johan, Sjöblom, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600027/
https://www.ncbi.nlm.nih.gov/pubmed/23496902
http://dx.doi.org/10.1186/1471-2164-14-165