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Quercetin Preserves β-Cell Mass and Function in Fructose-Induced Hyperinsulinemia through Modulating Pancreatic Akt/FoxO1 Activation

Fructose-induced hyperinsulinemia is associated with insulin compensative secretion and predicts the onset of type 2 diabetes. In this study, we investigated the preservation of dietary flavonoid quercetin on pancreatic β-cell mass and function in fructose-treated rats and INS-1 β-cells. Quercetin w...

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Detalles Bibliográficos
Autores principales: Li, Jian-Mei, Wang, Wei, Fan, Chen-Yu, Wang, Ming-Xing, Zhang, Xian, Hu, Qing-Hua, Kong, Ling-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600179/
https://www.ncbi.nlm.nih.gov/pubmed/23533474
http://dx.doi.org/10.1155/2013/303902