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Quercetin Preserves β-Cell Mass and Function in Fructose-Induced Hyperinsulinemia through Modulating Pancreatic Akt/FoxO1 Activation
Fructose-induced hyperinsulinemia is associated with insulin compensative secretion and predicts the onset of type 2 diabetes. In this study, we investigated the preservation of dietary flavonoid quercetin on pancreatic β-cell mass and function in fructose-treated rats and INS-1 β-cells. Quercetin w...
Autores principales: | Li, Jian-Mei, Wang, Wei, Fan, Chen-Yu, Wang, Ming-Xing, Zhang, Xian, Hu, Qing-Hua, Kong, Ling-Dong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600179/ https://www.ncbi.nlm.nih.gov/pubmed/23533474 http://dx.doi.org/10.1155/2013/303902 |
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