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Acute toxicity of vipoxin and its components: is the acidic component an “inhibitor” of PLA(2) toxicity?

Vipoxin is a heterodimeric neurotoxin isolated from the venom of the Bulgarian long-nosed viper Vipera ammodytes meridionalis. Vipoxin represents a noncovalent association of two subunits – a basic and toxic phospholipase A(2) enzyme, and an acidic non-enzymatic component (vipoxin's acidic comp...

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Detalles Bibliográficos
Autores principales: Atanasov, Vasil N., Stoykova, Silviya, Goranova, Yana, Mitewa, Mariana, Petrova, Svetla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Slovak Toxicology Society SETOX 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600519/
https://www.ncbi.nlm.nih.gov/pubmed/23554559
http://dx.doi.org/10.2478/v10102-012-0028-z