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Mathematical Optimization of the Combination of Radiation and Differentiation Therapies for Cancer

Cancer stem cells (CSC) are considered to be a major driver of cancer progression and successful therapies must control CSCs. However, CSC are often less sensitive to treatment and they might survive radiation and/or chemotherapies. In this paper we combine radiation treatment with differentiation t...

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Detalles Bibliográficos
Autores principales: Bachman, Jeff W. N., Hillen, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600539/
https://www.ncbi.nlm.nih.gov/pubmed/23508300
http://dx.doi.org/10.3389/fonc.2013.00052