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Dietary obesity-induced Egr-1 in adipocytes facilitates energy storage via suppression of FOXC2

The molecular mechanism to regulate energy balance is not completely understood. Here we observed that Egr-1 expression in white adipose tissue (WAT) was highly correlated with dietary-induced obesity and insulin resistance both in mice and humans. Egr-1 null mice were protected from diet-induced ob...

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Detalles Bibliográficos
Autores principales: Zhang, Jifeng, Zhang, Yuan, Sun, Tingwan, Guo, Fang, Huang, Shengping, Chandalia, Menisha, Abate, Nicola, Fan, Daping, Xin, Hong-Bo, Chen, Y. Eugene, Fu, Mingui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600596/
https://www.ncbi.nlm.nih.gov/pubmed/23502673
http://dx.doi.org/10.1038/srep01476