A Mathematical Model for the Rational Design of Chimeric Ligands in Selective Drug Therapies

Chimeric drugs with selective potential toward specific cell types constitute one of the most promising forefronts of modern Pharmacology. We present a mathematical model to test and optimize these synthetic constructs, as an alternative to conventional empirical design. We take as a case study a ch...

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Detalles Bibliográficos
Autores principales: Doldán-Martelli, V, Guantes, R, Míguez, D G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600755/
https://www.ncbi.nlm.nih.gov/pubmed/23887616
http://dx.doi.org/10.1038/psp.2013.2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600755/
https://www.ncbi.nlm.nih.gov/pubmed/23887616
http://dx.doi.org/10.1038/psp.2013.2

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