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A Mathematical Model for the Rational Design of Chimeric Ligands in Selective Drug Therapies
Chimeric drugs with selective potential toward specific cell types constitute one of the most promising forefronts of modern Pharmacology. We present a mathematical model to test and optimize these synthetic constructs, as an alternative to conventional empirical design. We take as a case study a ch...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600755/ https://www.ncbi.nlm.nih.gov/pubmed/23887616 http://dx.doi.org/10.1038/psp.2013.2 |