Cargando…

IL-1R1 is required for dendritic cell–mediated T cell reactivation within the CNS during West Nile virus encephalitis

Infections of the central nervous system (CNS) with cytopathic viruses require efficient T cell responses to promote viral clearance, limit immunopathology, and enhance survival. We found that IL-1R1 is critical for effector T cell reactivation and limits inflammation within the CNS during murine We...

Descripción completa

Detalles Bibliográficos
Autores principales: Durrant, Douglas M., Robinette, Michelle L., Klein, Robyn S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600909/
https://www.ncbi.nlm.nih.gov/pubmed/23460727
http://dx.doi.org/10.1084/jem.20121897