Innate Stat3-mediated induction of the antimicrobial protein Reg3γ is required for host defense against MRSA pneumonia

Pulmonary Staphylococcus aureus (SA) infections are a public health concern and a major complication of hyper-IgE syndrome, caused by mutations in STAT3. In contrast to previous findings of skin infection, we observed that clearance of SA from the lung did not require T, B, or NK cells but did requi...

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Detalles Bibliográficos
Autores principales: Choi, Sun-Mi, McAleer, Jeremy P., Zheng, Mingquan, Pociask, Derek A., Kaplan, Mark H., Qin, Shulin, Reinhart, Todd A., Kolls, Jay K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600913/
https://www.ncbi.nlm.nih.gov/pubmed/23401489
http://dx.doi.org/10.1084/jem.20120260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600913/
https://www.ncbi.nlm.nih.gov/pubmed/23401489
http://dx.doi.org/10.1084/jem.20120260

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