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Folic acid-tethered Pep-1 peptide-conjugated liposomal nanocarrier for enhanced intracellular drug delivery to cancer cells: conformational characterization and in vitro cellular uptake evaluation

BACKGROUND: A novel dual ligand–modified liposome, folic acid-tethered Pep-1 peptide-conjugated liposomal nanocarrier (FP-Lipo), was designed to overcome the nonselectivity of conventional penetrating peptide-tagged nanoparticulates and to provide the advantage of selective targeting of the folic ac...

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Detalles Bibliográficos
Autores principales: Kang, Myung Joo, Park, Sang Han, Kang, Mean Hyung, Park, Min Jung, Choi, Young Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600996/
https://www.ncbi.nlm.nih.gov/pubmed/23515421
http://dx.doi.org/10.2147/IJN.S39491