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Kupffer cell-mediated hepatic injury induced by silica nanoparticles in vitro and in vivo
Silica nanoparticles (SiO(2) NPs) have been shown to exert cytotoxic effects in hepato-cytes and to cause liver injury. In the liver, Kupffer cells (KCs), as the resident macrophages, play an important role in the normal physiology and homeostasis of the liver. Nevertheless, few studies have attempt...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600997/ https://www.ncbi.nlm.nih.gov/pubmed/23515466 http://dx.doi.org/10.2147/IJN.S42242 |