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Kupffer cell-mediated hepatic injury induced by silica nanoparticles in vitro and in vivo

Silica nanoparticles (SiO(2) NPs) have been shown to exert cytotoxic effects in hepato-cytes and to cause liver injury. In the liver, Kupffer cells (KCs), as the resident macrophages, play an important role in the normal physiology and homeostasis of the liver. Nevertheless, few studies have attempt...

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Detalles Bibliográficos
Autores principales: Chen, Qingqing, Xue, Yang, Sun, Jiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600997/
https://www.ncbi.nlm.nih.gov/pubmed/23515466
http://dx.doi.org/10.2147/IJN.S42242

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