Synergistic Effect of Afatinib with Su11274 in Non-Small Cell Lung Cancer Cells Resistant to Gefitinib or Erlotinib

Epidermal growth factor receptor (EGFR) and c-MET receptors are expressed on many non-small cell lung cancer (NSCLC) cells. Current single agent therapeutic targeting of a mutant EGFR has a high efficacy in the clinic, but is not curative. Here, we investigated the combination of targeting EGFR and...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Gang, Noor, Alfiah, Kronenberger, Peter, Teugels, Erik, Umelo, Ijeoma Adaku, De Grève, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601073/
https://www.ncbi.nlm.nih.gov/pubmed/23527257
http://dx.doi.org/10.1371/journal.pone.0059708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601073/
https://www.ncbi.nlm.nih.gov/pubmed/23527257
http://dx.doi.org/10.1371/journal.pone.0059708

Ejemplares similares