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Hypermethylation of Genes Detected in Urine from Ghanaian Adults with Bladder Pathology Associated with Schistosoma haematobium Infection

PURPOSE: Schistosoma haematobium is associated with chronic bladder damage and may subsequently induce bladder cancer in humans, thus posing a serious threat where the parasite is endemic. Here we evaluated aberrant promoter DNA methylation as a potential biomarker to detect severe bladder damage th...

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Detalles Bibliográficos
Autores principales: Zhong, Xiaoli, Isharwal, Sumit, Naples, Jean M., Shiff, Clive, Veltri, Robert W., Shao, Chunbo, Bosompem, Kwabena M., Sidransky, David, Hoque, Mohammad O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601097/
https://www.ncbi.nlm.nih.gov/pubmed/23527093
http://dx.doi.org/10.1371/journal.pone.0059089