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Induction of Thoracic Aortic Remodeling by Endothelial-Specific Deletion of MicroRNA-21 in Mice

MicroRNAs (miRs) are known to have an important role in modulating vascular biology. MiR21 was found to be involved in the pathogenesis of proliferative vascular disease. The role of miR21 in endothelial cells (ECs) has well studied in vitro, but the study in vivo remains to be elucidated. In this s...

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Detalles Bibliográficos
Autores principales: Zhang, Xing-Yi, Shen, Bao-Rong, Zhang, Yu-Cheng, Wan, Xue-Jiao, Yao, Qing-Ping, Wu, Guang-Liang, Wang, Ji-Yao, Chen, Si-Guo, Yan, Zhi-Qiang, Jiang, Zong-Lai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601125/
https://www.ncbi.nlm.nih.gov/pubmed/23527070
http://dx.doi.org/10.1371/journal.pone.0059002