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Co-expression of HIV-1 virus-like particles and granulocyte-macrophage colony stimulating factor by GEO-D03 DNA vaccine

Here, we report on GEO-D03, a DNA vaccine that co-expresses non-infectious HIV-1 virus-like particles (VLPs) and the human cytokine, granulocyte-macrophage colony-stimulating factor (GM-CSF). The virus-like particles display the native gp160 form of the HIV-1 Envelope glycoprotein (Env) and are desi...

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Detalles Bibliográficos
Autores principales: Hellerstein, Michael, Xu, Yongxian, Marino, Tracie, Lu, Shan, Yi, Hong, Wright, Elizabeth R., Robinson, Harriet L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601140/
https://www.ncbi.nlm.nih.gov/pubmed/23111169
http://dx.doi.org/10.4161/hv.21978