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Co-expression of HIV-1 virus-like particles and granulocyte-macrophage colony stimulating factor by GEO-D03 DNA vaccine
Here, we report on GEO-D03, a DNA vaccine that co-expresses non-infectious HIV-1 virus-like particles (VLPs) and the human cytokine, granulocyte-macrophage colony-stimulating factor (GM-CSF). The virus-like particles display the native gp160 form of the HIV-1 Envelope glycoprotein (Env) and are desi...
Autores principales: | Hellerstein, Michael, Xu, Yongxian, Marino, Tracie, Lu, Shan, Yi, Hong, Wright, Elizabeth R., Robinson, Harriet L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601140/ https://www.ncbi.nlm.nih.gov/pubmed/23111169 http://dx.doi.org/10.4161/hv.21978 |
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