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Effector memory regulatory T-cell expansion marks a pivotal point of immune escape in myelodysplastic syndromes

Myleodysplastic syndromes (MDS) are pre-malignant hematopoietic diseases that can progress to acute myeloid leukemia (AML) progression in conjunction with changes in immune function. In this model of leukemia evolution, the expansion of immunosuppressive regulatory T cells (Tregs) contributes to imm...

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Detalles Bibliográficos
Autores principales: Mailloux, Adam W., Epling-Burnette, Pearlie K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601152/
https://www.ncbi.nlm.nih.gov/pubmed/23524348
http://dx.doi.org/10.4161/onci.22654