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Effector memory regulatory T-cell expansion marks a pivotal point of immune escape in myelodysplastic syndromes
Myleodysplastic syndromes (MDS) are pre-malignant hematopoietic diseases that can progress to acute myeloid leukemia (AML) progression in conjunction with changes in immune function. In this model of leukemia evolution, the expansion of immunosuppressive regulatory T cells (Tregs) contributes to imm...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601152/ https://www.ncbi.nlm.nih.gov/pubmed/23524348 http://dx.doi.org/10.4161/onci.22654 |