Cargando…
Blockade of the PD-1 pathway enhances the efficacy of adoptive cell therapy against cancer
The blockade of the PD-1 pathway can increase the production of interferon γ by tumor-specific T cells located within or in the proximity of the malignant lesion, thereby increasing the chemokine-dependent trafficking of immune effector cells. This can boost the efficacy of adoptive T-cell therapy t...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601154/ https://www.ncbi.nlm.nih.gov/pubmed/23524510 http://dx.doi.org/10.4161/onci.22691 |