Myeloid-derived suppressor cells and the efficacy of CD8(+) T-cell immunotherapy

Myeloid-derived suppressor cells (MDSCs) promote immune evasion, a key feature of oncogenesis. The restoration of immunosurveillance by immunomodulatory antibodies improves the survival of a subset of cancer patients. Preclinical studies suggest that the ablation of monocytic MDSCs may be a useful a...

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Detalles Bibliográficos
Autores principales: Lesokhin, Alexander M., Merghoub, Taha, Wolchok, Jedd D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601158/
https://www.ncbi.nlm.nih.gov/pubmed/23525353
http://dx.doi.org/10.4161/onci.22764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601158/
https://www.ncbi.nlm.nih.gov/pubmed/23525353
http://dx.doi.org/10.4161/onci.22764

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