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How quantitative differences in dendritic cell maturation can direct T(H)1/T(H)2-cell polarization

The polarization of T(H)1 or T(H)2 responses by dendritic cells (DCs) requires distinct maturation conditions. Our data indicate that quantitative differences in DC maturation dictate a T(H1) or T(H)2-cell polarization outcome. We discuss how chromatin remodeling at DC loci coding for pro-inflammato...

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Detalles Bibliográficos
Autor principal: Lutz, Manfred B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601159/
https://www.ncbi.nlm.nih.gov/pubmed/23525517
http://dx.doi.org/10.4161/onci.22796