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The interaction between murine melanoma and the immune system reveals that prolonged responses predispose for autoimmunity

An assessment of antitumor immunity versus autoimmunity as provoked by the specific depletion of Foxp3(+) Tregs is now possible with the development of Foxp3-diphtheria toxin receptor-like transgenic mouse models. We have used the poorly immunogenic B16F10 melanoma model to characterize a very heter...

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Detalles Bibliográficos
Autores principales: Ngiow, Shin Foong, von Scheidt, Bianca, Möller, Andreas, Smyth, Mark J., Teng, Michele W. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601172/
https://www.ncbi.nlm.nih.gov/pubmed/23524369
http://dx.doi.org/10.4161/onci.23036