Trial watch: Cardiac glycosides and cancer therapy

Cardiac glycosides (CGs) are natural compounds sharing the ability to operate as potent inhibitors of the plasma membrane Na(+)/K(+)-ATPase, hence promoting—via an indirect mechanism—the intracellular accumulation of Ca(2+) ions. In cardiomyocytes, increased intracellular Ca(2+) concentrations exert...

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Detalles Bibliográficos
Autores principales: Menger, Laurie, Vacchelli, Erika, Kepp, Oliver, Eggermont, Alexander, Tartour, Eric, Zitvogel, Laurence, Kroemer, Guido, Galluzzi, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601180/
https://www.ncbi.nlm.nih.gov/pubmed/23525565
http://dx.doi.org/10.4161/onci.23082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601180/
https://www.ncbi.nlm.nih.gov/pubmed/23525565
http://dx.doi.org/10.4161/onci.23082

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