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EdU induces DNA damage response and cell death in mESC in culture

Recently, a novel DNA replication precursor analogue called 5-ethynyl-2′-deoxyuridine (EdU) has been widely used to monitor DNA synthesis as an alternative to bromodeoxyuridine. Use of EdU benefits from simplicity and reproducibility and the simple chemical detection systems allows excellent preserv...

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Detalles Bibliográficos
Autores principales: Kohlmeier, Fanni, Maya-Mendoza, Apolinar, Jackson, Dean A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601257/
https://www.ncbi.nlm.nih.gov/pubmed/23463495
http://dx.doi.org/10.1007/s10577-013-9340-5