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Vps35 loss promotes hyperresorptive osteoclastogenesis and osteoporosis via sustained RANKL signaling

Receptor activator of NF-κB (RANK) plays a critical role in osteoclastogenesis, an essential process for the initiation of bone remodeling to maintain healthy bone mass and structure. Although the signaling and function of RANK have been investigated extensively, much less is known about the negativ...

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Detalles Bibliográficos
Autores principales: Xia, Wen-Fang, Tang, Fu-Lei, Xiong, Lei, Xiong, Shan, Jung, Ji-Ung, Lee, Dae-Hoon, Li, Xing-Sheng, Feng, Xu, Mei, Lin, Xiong, Wen-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601351/
https://www.ncbi.nlm.nih.gov/pubmed/23509071
http://dx.doi.org/10.1083/jcb.201207154